Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus.

Modified oligodeoxynucleotides complementary to RNA of human immunodeficiency virus 1 (HIV-1) were tested for their ability to inhibit virally induced syncytium formation and expression of viral p24 protein. The modifications of oligomers include replacement of backbone phosphodiester groups with ph...

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Autores principales: Agrawal, S, Goodchild, J, Civeira, M P, Thornton, A H, Sarin, P S, Zamecnik, P C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC282127/
https://ncbi.nlm.nih.gov/pubmed/3174622
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