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Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus.

Modified oligodeoxynucleotides complementary to RNA of human immunodeficiency virus 1 (HIV-1) were tested for their ability to inhibit virally induced syncytium formation and expression of viral p24 protein. The modifications of oligomers include replacement of backbone phosphodiester groups with ph...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Agrawal, S, Goodchild, J, Civeira, M P, Thornton, A H, Sarin, P S, Zamecnik, P C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7079
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