Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene

Variations of the corticotropin-releasing hormone receptor 1 (CRHR1) gene appear to moderate the development of depression after childhood trauma. Depression more frequently affects women than men. We examined sex differences in the effects of the CRHR1 gene on the relationship between childhood tra...

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Detalhes bibliográficos
Main Authors: Heim, Christine, Bradley, Bekh, Mletzko, Tanja C., Deveau, Todd C., Musselman, Dominique L., Nemeroff, Charles B., Ressler, Kerry J., Binder, Elisabeth B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2009
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821197/
https://ncbi.nlm.nih.gov/pubmed/20161813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/neuro.08.041.2009
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