Polymorphisms in CRHR1 and the Serotonin Transporter Loci: Gene × Gene × Environment Interactions on Depressive Symptoms

Gene × environment (G × E) interactions mediating depressive symptoms have been separately identified in the stress-sensitive serotonergic (5-HTTLPR) and corticotropin-releasing hormone (CRHR1) systems. Our objective was to examine whether the effects of child abuse are moderated by gene × gene (G ×...

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Detalhes bibliográficos
Main Authors: Ressler, Kerry J, Bradley, Bekh, Mercer, Kristina B, Deveau, Todd C, Smith, Alicia K, Gillespie, Charles F, Nemeroff, Charles B, Cubells, Joseph F, Binder, Elisabeth B
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924813/
https://ncbi.nlm.nih.gov/pubmed/20029939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.31052
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