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Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

Although the fact that genetic predisposition and environmental exposures interact to shape development and function of the human brain and, ultimately, the risk of psychiatric disorders has drawn wide interest, the corresponding molecular mechanisms have not yet been elucidated. We found that a fun...

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Detalhes bibliográficos
Main Authors: Klengel, Torsten, Mehta, Divya, Anacker, Christoph, Rex-Haffner, Monika, Pruessner, Jens C, Pariante, Carmine M, Pace, Thaddeus W W, Mercer, Kristina B, Mayberg, Helen S, Bradley, Bekh, Nemeroff, Charles B, Holsboer, Florian, Heim, Christine M, Ressler, Kerry J, Rein, Theo, Binder, Elisabeth B
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136922/
https://ncbi.nlm.nih.gov/pubmed/23201972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3275
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