Using Polymorphisms in FKBP5 to Define Biologically Distinct Subtypes of Posttraumatic Stress Disorder: Evidence From Endocrine and Gene Expression Studies

CONTEXT: Polymorphisms in the gene encoding the glucocorticoid receptor (GR) regulating co-chaperone FKBP5 have been shown to alter GR sensitivity and are associated with an increased risk to develop posttraumatic stress disorder (PTSD). OBJECTIVE: To investigate interactions of the FKBP5 single-nuc...

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Main Authors: Mehta, Divya, Gonik, Mariya, Klengel, Torsten, Rex-Haffner, Monika, Menke, Andreas, Rubel, Jennifer, Mercer, Kristina B., Pütz, Benno, Bradley, Bekh, Holsboer, Florian, Ressler, Kerry J., Müller-Myhsok, Bertram, Binder, Elisabeth B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686481/
https://ncbi.nlm.nih.gov/pubmed/21536970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2011.50
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