Sex differences in the TLR-mediated response of pDCs to HIV-1 are associated with higher immune activation in infected women

Manifestations of viral infections can differ between women and men1, and significant sex differences have been described in the course of HIV-1 disease. HIV-1-infected women tend to have lower viral load levels early in HIV-1 infection, but progress faster to AIDS for a given viral load than men2–7...

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Main Authors: Meier, Angela, Chang, J. Judy, Chan, Ellen S., Pollard, Richard B., Sidhu, Harlyn K., Kulkarni, Smita, Wen, Tom Fang, Lindsay, Robert J., Orellana, Liliana, Mildvan, Donna, Bazner, Suzane, Streeck, Hendrik, Alter, Galit, Lifson, Jeffrey D., Carrington, Mary, Bosch, Ronald J., Robbins, Gregory K., Altfeld, Marcus
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821111/
https://ncbi.nlm.nih.gov/pubmed/19597505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2004
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