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Up-regulation of PD-L1 on Monocytes and Dendritic Cells by HIV-1 derived TLR Ligands
Increased PD-L1 expression has been reported in HIV-1-infected individuals, but the mechanisms leading to PD-L1-up-regulation remain to be elucidated. Here we demonstrate that HIV-1-derived TLR7/8 ligands can induce MyD88-dependent up-regulation of PD-L1 on pDCs, mDCs and monocytes. These data sugge...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810187/ https://ncbi.nlm.nih.gov/pubmed/18317010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3282f4de23 |
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