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Sequestration of Free Tubulin Molecules by the Viral Protein NSP2 Induces Microtubule Depolymerization during Rotavirus Infection

Microtubules, components of the cell cytoskeleton, play a central role in cellular trafficking. Here we show that rotavirus infection leads to a remodeling of the microtubule network together with the formation of tubulin granules. While most microtubules surrounding the nucleus depolymerize, others...

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Detalhes bibliográficos
Main Authors: Martin, Davy, Duarte, Mariela, Lepault, Jean, Poncet, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820929/
https://ncbi.nlm.nih.gov/pubmed/20032187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01883-09
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