Dominant-Lethal α-Tubulin Mutants Defective in Microtubule Depolymerization in Yeast
The dynamic instability of microtubules has long been understood to depend on the hydrolysis of GTP bound to β-tubulin, an event stimulated by polymerization and necessary for depolymerization. Crystallographic studies of tubulin show that GTP is bound by β-tubulin at the longitudinal dimer-dimer in...
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| 发表在: | Mol Biol Cell |
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| Principais autores: | , |
| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
American Society for Cell Biology
2001
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| 主题: | |
| 在线阅读: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739794/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.12.3973 |
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