Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex

Through its interaction with the 5′ translation initiation factor eIF4G, poly(A) binding protein (PABP) facilitates the translation of 5′-capped and 3′-poly(A)-tailed mRNAs. Rotavirus mRNAs are capped but not polyadenylated, instead terminating in a 3′ GACC motif that is recognized by the viral prot...

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Publicat a:J Virol
Autors principals: Gratia, Matthieu, Sarot, Emeline, Vende, Patrice, Charpilienne, Annie, Baron, Carolina Hilma, Duarte, Mariela, Pyronnet, Stephane, Poncet, Didier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524085/
https://ncbi.nlm.nih.gov/pubmed/26063427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01402-15
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