ICP27 Phosphorylation Site Mutants Are Defective in Herpes Simplex Virus 1 Replication and Gene Expression

Herpes simplex virus 1 (HSV-1) protein ICP27 is a multifunctional regulatory protein that is posttranslationally modified by phosphorylation during viral infection. ICP27 has been shown to be phosphorylated on three serine residues, specifically serine residues 16 and 18, which are within casein kin...

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Autores principales: Rojas, Santos, Corbin-Lickfett, Kara A., Escudero-Paunetto, Laurimar, Sandri-Goldin, Rozanne M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820901/
https://ncbi.nlm.nih.gov/pubmed/20015991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00917-09
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