Activation of the Ran GTPase Is Subject to Growth Factor Regulation and Can Give Rise to Cellular Transformation

Although the small GTPase Ran is best known for its roles in nucleocytoplasmic transport, mitotic spindle assembly, and nuclear envelope formation, recent studies have demonstrated the overexpression of Ran in multiple tumor types and that its expression is correlated with a poor patient prognosis,...

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Detalhes bibliográficos
Main Authors: Ly, Thi K., Wang, Jianbin, Pereira, Ryan, Rojas, Katherine S., Peng, Xu, Feng, Qiyu, Cerione, Richard A., Wilson, Kristin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820807/
https://ncbi.nlm.nih.gov/pubmed/20028979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071886
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