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Characterization of a Novel Activated Ran GTPase Mutant and Its Ability to Induce Cellular Transformation

Ran (Ras-related nuclear) protein, a member of the Ras superfamily of GTPases, is best known for its roles in nucleocytoplasmic transport, mitotic spindle fiber assembly, and nuclear envelope formation. Recently, we have shown that the overexpression of Ran in fibroblasts induces cellular transforma...

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Detalhes bibliográficos
Main Authors: Milano, Shawn K., Kwon, Woojin, Pereira, Ryan, Antonyak, Marc A., Cerione, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408178/
https://ncbi.nlm.nih.gov/pubmed/22679017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.306514
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