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Vaccinia Virus Protein F1L Is a Caspase-9 Inhibitor

Apoptosis plays important roles in host defense, including the elimination of virus-infected cells. The executioners of apoptosis are caspase family proteases. We report that vaccinia virus-encoded F1L protein, previously recognized as anti-apoptotic viral Bcl-2 family protein, is a caspase-9 inhibi...

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מידע ביבליוגרפי
Main Authors: Zhai, Dayong, Yu, Eric, Jin, Chaofang, Welsh, Kate, Shiau, Chung-wei, Chen, Lili, Salvesen, Guy S., Liddington, Robert, Reed, John C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820784/
https://ncbi.nlm.nih.gov/pubmed/20022954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078113
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