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Regulation of Vascular Endothelial Growth Factor (VEGF) Splicing from Pro-angiogenic to Anti-angiogenic Isoforms: A NOVEL THERAPEUTIC STRATEGY FOR ANGIOGENESIS
Vascular endothelial growth factor (VEGF) is produced either as a pro-angiogenic or anti-angiogenic protein depending upon splice site choice in the terminal, eighth exon. Proximal splice site selection (PSS) in exon 8 generates pro-angiogenic isoforms such as VEGF(165), and distal splice site selec...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Biochemistry and Molecular Biology
2010
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820781/ https://ncbi.nlm.nih.gov/pubmed/19906640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074930 |
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