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Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

Vascular endothelial growth factor A (VEGFA; hereafter referred to as VEGF) is a key regulator of physiological and pathological angiogenesis. Two families of VEGF isoforms are generated by alternate splice-site selection in the terminal exon. Proximal splice-site selection (PSS) in exon 8 results i...

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Autori principali: Nowak, Dawid G., Woolard, Jeanette, Amin, Elianna Mohamed, Konopatskaya, Olga, Saleem, Moin A., Churchill, Amanda J., Ladomery, Michael R., Harper, Steven J., Bates, David O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613349/
https://ncbi.nlm.nih.gov/pubmed/18843117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.016410
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