Isolation and Characterization of Cytoplasmic Cofilin-Actin Rods

Cofilin-actin bundles (rods), which form in axons and dendrites of stressed neurons, lead to synaptic dysfunction and may mediate cognitive deficits in dementias. Rods form abundantly in the cytoplasm of non-neuronal cells in response to many treatments that induce rods in neurons. Rods in cell lysa...

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Bibliographic Details
Main Authors: Minamide, Laurie S., Maiti, Sankar, Boyle, Judith A., Davis, Richard C., Coppinger, Judith A., Bao, Yunhe, Huang, Timothy Y., Yates, John, Bokoch, Gary M., Bamburg, James R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820773/
https://ncbi.nlm.nih.gov/pubmed/20022956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063768
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