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Regulation of Bim in Glucocorticoid-Mediated Osteoblast Apoptosis

Osteoblasts undergo apoptosis both in vitro and in vivo in response to high dose glucocorticoid (GC) treatment. However, the molecular mechanisms remain elusive, hindering the prevention and treatment of this side-effect. Apoptosis was induced by dexamethasone (Dex) in murine MBA-15.4 osteoblasts wi...

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Hlavní autoři: ESPINA, B., LIANG, M., RUSSELL, R.G.G., HULLEY, P.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820732/
https://ncbi.nlm.nih.gov/pubmed/18064628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21335
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