Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo

Skeletal mass is maintained by a balance between formation and resorption, cell proliferation and apoptosis. In vitro, glucocorticoids (GCs) decrease extracellular signal-regulated kinases (ERK) activation by mitogens, thus inhibiting osteoblast proliferation. Both ERK activity and proliferation are...

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Detalhes bibliográficos
Main Authors: Conradie, M M, de Wet, H, Kotze, D D R, Burrin, J M, Hough, F S, Hulley, P A
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Endocrinology 2007
Assuntos:
Regular Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173947/
https://ncbi.nlm.nih.gov/pubmed/17951534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-07-0217
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