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The Lysosomal Sialic Acid Transporter Sialin Is Required for Normal CNS Myelination

Salla disease and infantile sialic acid storage disease are autosomal recessive lysosomal storage disorders caused by mutations in the gene encoding sialin, a membrane protein that transports free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation. A...

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Detalles Bibliográficos
Main Authors: Prolo, Laura M., Vogel, Hannes, Reimer, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820501/
https://ncbi.nlm.nih.gov/pubmed/20007460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3005-09.2009
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