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β1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth
Oligodendrocytes in the central nervous system (CNS) produce myelin sheaths that insulate axons to ensure fast propagation of action potentials. β1 integrins regulate the myelination of peripheral nerves, but their function during the myelination of axonal tracts in the CNS is unclear. Here we show...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Company of Biologists
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730401/ https://ncbi.nlm.nih.gov/pubmed/19633169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.038679 |
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