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β1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth

Oligodendrocytes in the central nervous system (CNS) produce myelin sheaths that insulate axons to ensure fast propagation of action potentials. β1 integrins regulate the myelination of peripheral nerves, but their function during the myelination of axonal tracts in the CNS is unclear. Here we show...

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Detalles Bibliográficos
Main Authors: Barros, Claudia S., Nguyen, Tom, Spencer, Kathryn S. R., Nishiyama, Akiko, Colognato, Holly, Müller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730401/
https://ncbi.nlm.nih.gov/pubmed/19633169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.038679
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