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β1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth

Oligodendrocytes in the central nervous system (CNS) produce myelin sheaths that insulate axons to ensure fast propagation of action potentials. β1 integrins regulate the myelination of peripheral nerves, but their function during the myelination of axonal tracts in the CNS is unclear. Here we show...

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Bibliografske podrobnosti
Main Authors: Barros, Claudia S., Nguyen, Tom, Spencer, Kathryn S. R., Nishiyama, Akiko, Colognato, Holly, Müller, Ulrich
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730401/
https://ncbi.nlm.nih.gov/pubmed/19633169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.038679
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