Double-stranded RNA-dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis

As chronic inflammation is a hallmark of obesity, pathways that integrate nutrient and pathogen sensing pathways are of great interest in understanding the mechanisms of insulin resistance, type 2 diabetes, and other chronic metabolic pathologies. Here, we provide evidence that double-stranded RNA d...

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Autors principals: Nakamura, Takahisa, Furuhashi, Masato, Li, Ping, Cao, Haiming, Tuncman, Gurol, Sonenberg, Nahum, Gorgun, Cem Z., Hotamisligil, Gökhan S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820414/
https://ncbi.nlm.nih.gov/pubmed/20144759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.01.001
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