Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification

Immunity to one of the four dengue virus (DV) serotypes can increase disease severity in humans upon subsequent infection with another DV serotype. Serotype cross-reactive antibodies facilitate DV infection of myeloid cells in vitro by promoting virus entry via Fcγ receptors (FcγR), a process known...

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書誌詳細
主要な著者: Balsitis, Scott J., Williams, Katherine L., Lachica, Ruben, Flores, Diana, Kyle, Jennifer L., Mehlhop, Erin, Johnson, Syd, Diamond, Michael S., Beatty, P. Robert, Harris, Eva
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820409/
https://ncbi.nlm.nih.gov/pubmed/20168989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000790
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