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Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification
Immunity to one of the four dengue virus (DV) serotypes can increase disease severity in humans upon subsequent infection with another DV serotype. Serotype cross-reactive antibodies facilitate DV infection of myeloid cells in vitro by promoting virus entry via Fcγ receptors (FcγR), a process known...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820409/ https://ncbi.nlm.nih.gov/pubmed/20168989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000790 |
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