Essential Role of the Histone Methyltransferase G9a in Cocaine-induced Plasticity

Cocaine-induced alterations in gene expression cause changes in neuronal morphology and behavior that may underlie cocaine addiction. We identified an essential role for histone 3 lysine 9 (H3K9) dimethylation and the lysine dimethyltransferase G9a in cocaine-induced structural and behavioral plasti...

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Detalhes bibliográficos
Main Authors: Maze, Ian, Covington, Herbert E., Dietz, David M., LaPlant, Quincey, Renthal, William, Russo, Scott J., Mechanic, Max, Mouzon, Ezekiell, Neve, Rachael L., Haggarty, Stephen J., Ren, Yanhua, Sampath, Srihari C., Hurd, Yasmin L., Greengard, Paul, Tarakhovsky, Alexander, Schaefer, Anne, Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820240/
https://ncbi.nlm.nih.gov/pubmed/20056891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1179438
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