Pro-angiogenic effect of IFNγ is dependent on the PI3K/mTOR/translational pathway in human retinal pigmented epithelial cells

PURPOSE: To investigate the molecular signaling pathway of Interferon gamma (IFNγ) contributing to angiogenesis in retinal pigmented epithelial (RPE) cells and the role of Phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) in this process. METHODS: Human adult and fetal RPE cells...

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Hlavní autoři: Liu, Baoying, Faia, Lisa, Hu, Mengjun, Nussenblatt, Robert B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Vision 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820105/
https://ncbi.nlm.nih.gov/pubmed/20157617
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