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Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

Oxidative damage to DNA can be caused by excited oxygen species, which are produced by radiation or are by-products of aerobic metabolism. The oxidized base, 8-hydroxydeoxyguanosine (oh8dG), 1 of approximately 20 known radiation damage products, has been assayed in the DNA of rat liver. oh8dG is pre...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Richter, C, Park, J W, Ames, B N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.17.6465
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