Normal oxidative damage to mitochondrial and nuclear DNA is extensive.
Oxidative damage to DNA can be caused by excited oxygen species, which are produced by radiation or are by-products of aerobic metabolism. The oxidized base, 8-hydroxydeoxyguanosine (oh8dG), 1 of approximately 20 known radiation damage products, has been assayed in the DNA of rat liver. oh8dG is pre...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1988
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.17.6465 |
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