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Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

Oxidative damage to DNA can be caused by excited oxygen species, which are produced by radiation or are by-products of aerobic metabolism. The oxidized base, 8-hydroxydeoxyguanosine (oh8dG), 1 of approximately 20 known radiation damage products, has been assayed in the DNA of rat liver. oh8dG is pre...

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Detalhes bibliográficos
Main Authors: Richter, C, Park, J W, Ames, B N
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC281993/
https://ncbi.nlm.nih.gov/pubmed/3413108
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