Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis

Rapid neurotransmitter release depends on the ability to arrest the SNAP receptor (SNARE)–dependent exocytosis pathway at an intermediate “cocked” state, from which fusion can be triggered by Ca(2+). It is not clear whether this state includes assembly of synaptobrevin (the vesicle membrane SNARE) t...

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Bibliografiske detaljer
Main Authors: Walter, Alexander M., Wiederhold, Katrin, Bruns, Dieter, Fasshauer, Dirk, Sørensen, Jakob B.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819690/
https://ncbi.nlm.nih.gov/pubmed/20142423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200907018
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