Alpha-Synuclein Abnormalities in Mouse Models of Peroxisome Biogenesis Disorders

alpha-Synuclein (αS) is a presynaptic protein implicated in Parkinson’s disease (PD). Growing evidence implicates mitochondrial dysfunction, oxidative stress and αS-lipids interactions in the gradual accumulation of αS in pathogenic forms and its deposition in Lewy bodies, the pathological hallmark...

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Main Authors: Yakunin, Eugenia, Moser, Ann, Loeb, Virginie, Reisch, Ann Saada, Faust, Phyllis, Crane, Denis I., Baes, Myriam, Sharon, Ronit
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819671/
https://ncbi.nlm.nih.gov/pubmed/19830841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22246
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