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The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders

Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal matrix protein import. Mutations in...

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Bibliographic Details
Published in:Autophagy
Main Authors: Law, Kelsey B., Bronte-Tinkew, Dana, Di Pietro, Erminia, Snowden, Ann, Jones, Richard O., Moser, Ann, Brumell, John H., Braverman, Nancy, Kim, Peter K.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446072/
https://ncbi.nlm.nih.gov/pubmed/28521612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1291470
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