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Use of Drosophila Deoxynucleoside Kinase to Study Mechanism of Toxicity and Mutagenicity of Deoxycytidine Analogs in Escherichia coli
Most bacteria, including Escherichia coli, lack an enzyme that can phosphorylate deoxycytidine and its analogs. Consequently, most studies of toxicity and mutagenicity of cytosine analogs u se ribonucleosides such as 5-azacytidine (AzaC) and zebularine (Zeb) instead of their deoxynucleoside forms, 5...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819640/ https://ncbi.nlm.nih.gov/pubmed/20005183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.11.006 |
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