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WHEP Domains Direct Noncanonical Function of Glutamyl-Prolyl tRNA Synthetase in Translational Control of Gene Expression
Expression of inflammatory genes is often regulated by translational control mechanisms. The heterotetrameric GAIT complex suppresses translation of selected mRNAs in interferon-γ-activated monocytic cells. Specificity is dictated by glutamyl-prolyl tRNA synthetase (EPRS) binding to a 3'UTR ele...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819395/ https://ncbi.nlm.nih.gov/pubmed/18374644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.01.010 |
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