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BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression

The B cell leukemia 11A protein (BCL11A/Evi9/CTIP1) has been implicated in hematopoietic cell development and malignancies. BCL11A is a transcriptional repressor that binds directly to a GC-rich motif and is also recruited to a promoter template via interaction with the orphan nuclear receptor, chic...

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Main Authors: Senawong, Thanaset, Peterson, Valerie J., Leid, Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819353/
https://ncbi.nlm.nih.gov/pubmed/15639232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2004.10.028
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