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The Ca(2+ )activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro
BACKGROUND: Small-conductance Ca(2+ )activated K(+ )channels are expressed in the CNS, where KCNN2/SK2/KCa2.2 and KCNN3/SK3/KCa2.3 help shape the electrical activity of some neurons. The SK3 channel is considered a potential therapeutic target for diseases and disorders involving neuron hyper-excita...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819255/ https://ncbi.nlm.nih.gov/pubmed/20074365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-4 |
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