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Reprogramming of Pancreatic β Cells into Induced Pluripotent Stem Cells

Induced pluripotent stem (iPS) cells have been derived from fibroblast, stomach, and liver cultures at extremely low frequencies by ectopic expression of the transcription factors Oct4, Sox2, c-myc, and Klf4, a process coined direct or in vitro reprogramming [1–8]. iPS cells are molecularly and func...

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Autori principali: Stadtfeld, Matthias, Brennand, Kristen, Hochedlinger, Konrad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819222/
https://ncbi.nlm.nih.gov/pubmed/18501604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.05.010
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