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Rescue of Developmental Defects by Blastocyst Stem Cell Injection: Towards Elucidation of Neomorphic Corrective Pathways

Stem cell-based therapy is an exciting area of high potential for regenerative medicine. To study disease prevention, we inject mouse embryonic stem cells (ESCs) into a variety of mouse blastocysts, most of which harbor mutations. Mice derived from these mutant blastocysts develop human-like disease...

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Detalhes bibliográficos
Main Authors: Zhao, Qingshi, Beck, Amanda, Vitale, Joseph M., Schneider, Joel S., Terzic, Andre, Fraidenraich, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819177/
https://ncbi.nlm.nih.gov/pubmed/20151025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-009-9140-7
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