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Rescue of cardiac defects in Id knockout embryos by injection of embryonic stem cells
We report that Id knockout mouse embryos display multiple cardiac defects but mid-gestation lethality is rescued by injection of 15 wild type ES cells into mutant blastocysts. Myocardial markers altered in Id mutant cells are restored to normal throughout the chimeric myocardium. Intraperitoneal inj...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351017/ https://ncbi.nlm.nih.gov/pubmed/15472070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1102612 |
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