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Rac Activation: P-Rex1 — A Convergence Point for PIP(3) and Gβγ?
P-Rex1, a novel Rac activator, has been identified in the first biochemical purification of a guanine nucleotide exchange factor for GTPases of the Rho family. P-Rex1 is synergistically activated by PIP(3) and Gβγ and may act as a coincidence detector for these signaling molecules.
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819105/ https://ncbi.nlm.nih.gov/pubmed/12123595 |
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