Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase (AEP)

Ischemia and seizure cause excessive neuronal excitation that is associated with brain acidosis and neuronal cell death. However, the molecular mechanism of acidification-triggered neuronal injury is incompletely understood. Here, we show that Asparagine Endopeptidase (AEP) is activated under acidic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Zhixue, Jang, Sung-Wuk, Liu, Xia, Cheng, Dongmei, Peng, Junmin, Yepes, Maneul, Li, Xiao-jiang, Matthews, Steve, Watts, Colin, Asano, Masahide, Hara-Nishimura, Ikuko, Luo, Hongbo R., Ye, Keqiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819101/
https://ncbi.nlm.nih.gov/pubmed/18374643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.02.017
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