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How Telomeres Solve the End-Protection Problem

The ends of eukaryotic chromosomes have the potential to be mistaken for damaged or broken DNA and must therefore be protected from cellular DNA damage response pathways. Otherwise, cells might permanently arrest in the cell cycle, and attempts to “repair” the chromosome ends would have devastating...

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Bibliografische gegevens
Hoofdauteur: de Lange, Titia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819049/
https://ncbi.nlm.nih.gov/pubmed/19965504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170633
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