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How Telomeres Solve the End-Protection Problem
The ends of eukaryotic chromosomes have the potential to be mistaken for damaged or broken DNA and must therefore be protected from cellular DNA damage response pathways. Otherwise, cells might permanently arrest in the cell cycle, and attempts to “repair” the chromosome ends would have devastating...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819049/ https://ncbi.nlm.nih.gov/pubmed/19965504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170633 |
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