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How Telomeres Solve the End-Protection Problem

The ends of eukaryotic chromosomes have the potential to be mistaken for damaged or broken DNA and must therefore be protected from cellular DNA damage response pathways. Otherwise, cells might permanently arrest in the cell cycle, and attempts to “repair” the chromosome ends would have devastating...

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Détails bibliographiques
Auteur principal: de Lange, Titia
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819049/
https://ncbi.nlm.nih.gov/pubmed/19965504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170633
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