Staphylococcus aureus evades the lysozyme-based digestion of peptidoglycan that links phagocytosis and macrophage IL-1β secretion

IL-1β produced by phagocytes is important for protection against Staphylococcus aureus. Secretion of this cytokine requires both activation of a transcriptional signal to stimulate production of pro-IL-1β, and a second signal to stimulate processing by inflammasome complexes and release of the matur...

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Detalhes bibliográficos
Main Authors: Shimada, Takahiro, Park, Bong Goo, Wolf, Andrea J., Brikos, Constantinos, Goodridge, Helen S., Becker, Courtney A., Reyes, Christopher N., Miao, Edward A., Aderem, Alan, Götz, Friedrich, Liu, George Y., Underhill, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818986/
https://ncbi.nlm.nih.gov/pubmed/20114027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.12.008
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