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Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice

Streptococcus pneumoniae colonizes the mucosal surface of the human upper respiratory tract. A colonization event is gradually cleared through phagocytosis by monocytes/macrophages that are recruited to the airway lumen. Here, we sought to define the bacterial and host factors that promote monocyte/...

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Detalhes bibliográficos
Main Authors: Davis, Kimberly M., Nakamura, Shigeki, Weiser, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163965/
https://ncbi.nlm.nih.gov/pubmed/21841315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57761
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