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CCR5-ligands modulate CXCL12 induced chemotaxis, adhesion and Akt phosphorylation of human cord blood CD34+ cells
C-X-C motif ligand12 (CXCL12) and its receptor, CXCR4, play an important role in hematopoietic stem/progenitor cells’ (HSPCs) migration from and retention within the bone marrow. HSPCs are very selective in their chemotactic response and undergo chemotaxis only in response to CXCL12. In addition to...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818985/ https://ncbi.nlm.nih.gov/pubmed/19917679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900542 |
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