β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7

Ubiquitously expressed seven-transmembrane receptors (7TMRs) classically signal through heterotrimeric G proteins and are commonly referred to as G protein-coupled receptors. It is now recognized that 7TMRs also signal through β-arrestins, which act as versatile adapters controlling receptor signali...

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Bibliografiska uppgifter
Huvudupphovsmän: Rajagopal, Sudarshan, Kim, Jihee, Ahn, Seungkirl, Craig, Stewart, Lam, Christopher M., Gerard, Norma P., Gerard, Craig, Lefkowitz, Robert J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818968/
https://ncbi.nlm.nih.gov/pubmed/20018651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912852107
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