Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.

Formation of retinoblastoma, a cancer arising in the retinas of young children, is determined by mutational inactivation of an autosomal gene (RB), which has been molecularly cloned. Whereas all normal tissues and many tumor cells express an RB mRNA of 4.7 kilobases, six of six retinoblastomas were...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Lee, E Y, Bookstein, R, Young, L J, Lin, C J, Rosenfeld, M G, Lee, W H
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1988
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413073/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6017
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