Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.

Formation of retinoblastoma, a cancer arising in the retinas of young children, is determined by mutational inactivation of an autosomal gene (RB), which has been molecularly cloned. Whereas all normal tissues and many tumor cells express an RB mRNA of 4.7 kilobases, six of six retinoblastomas were...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Lee, E Y, Bookstein, R, Young, L J, Lin, C J, Rosenfeld, M G, Lee, W H
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413073/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6017
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